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Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype Maps

High-order epistasis has been observed in many genotype-phenotype maps. These multi-way interactions between mutations may be useful for dissecting complex traits and could have profound implications for evolution. Alternatively, they could be a statistical artifact. High-order epistasis models assu...

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Detalles Bibliográficos
Autores principales:	Sailer, Zachary R., Harms, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340324/ https://www.ncbi.nlm.nih.gov/pubmed/28100592 http://dx.doi.org/10.1534/genetics.116.195214

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