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Smad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts

The potential involvement of connective tissue growth factor (CCN2/CTGF) in extracellular matrix (ECM) production is recognized. However, the role CCN2 in fibronectin (FN) gene expression has remained incompletely understood and even controversial. Here we report that CCN2 is absolutely necessary fo...

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Detalles Bibliográficos
Autores principales: Purohit, Trupta, Qin, Zhaoping, Quan, Chunji, Lin, Zhenhua, Quan, Taihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340390/
https://www.ncbi.nlm.nih.gov/pubmed/28267785
http://dx.doi.org/10.1371/journal.pone.0173191