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Smad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts
The potential involvement of connective tissue growth factor (CCN2/CTGF) in extracellular matrix (ECM) production is recognized. However, the role CCN2 in fibronectin (FN) gene expression has remained incompletely understood and even controversial. Here we report that CCN2 is absolutely necessary fo...
Autores principales: | Purohit, Trupta, Qin, Zhaoping, Quan, Chunji, Lin, Zhenhua, Quan, Taihao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340390/ https://www.ncbi.nlm.nih.gov/pubmed/28267785 http://dx.doi.org/10.1371/journal.pone.0173191 |
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