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Active zone proteins are transported via distinct mechanisms regulated by Par-1 kinase

Disruption of synapses underlies a plethora of neurodevelopmental and neurodegenerative disease. Presynaptic specialization called the active zone plays a critical role in the communication with postsynaptic neuron. While the role of many proteins at the active zones in synaptic communication is rel...

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Detalles Bibliográficos
Autores principales: Barber, Kara R., Tanquary, Julia, Bush, Keegan, Shaw, Amanda, Woodson, Michael, Sherman, Michael, Wairkar, Yogesh P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340405/
https://www.ncbi.nlm.nih.gov/pubmed/28222093
http://dx.doi.org/10.1371/journal.pgen.1006621