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Enforced Expression of CXCR5 Drives T Follicular Regulatory-Like Features in Foxp3(+) T Cells

CXCR5(+) T follicular helper (Tfh) cells are associated with aberrant autoantibody production in patients with antibody-mediated autoimmune diseases including lupus. Follicular regulatory T (Tfr) cells expressing CXCR5 and Bcl6 have been recently identified as a specialized subset of Foxp3(+) regula...

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Detalles Bibliográficos
Autores principales: Kim, Young Uk, Kim, Byung-Seok, Lim, Hoyong, Wetsel, Rick A., Chung, Yeonseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340537/
https://www.ncbi.nlm.nih.gov/pubmed/27737526
http://dx.doi.org/10.4062/biomolther.2016.075