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Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit

Metabolic engineering of microorganisms to produce desirable products on an industrial scale can result in unbalanced cellular metabolic networks that reduce productivity and yield. Metabolic fluxes can be rebalanced using dynamic pathway regulation, but few broadly applicable tools are available to...

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Detalles Bibliográficos
Autores principales: Gupta, Apoorv, Brockman Reizman, Irene M., Reisch, Christopher R., Prather, Kristala L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340623/
https://www.ncbi.nlm.nih.gov/pubmed/28191902
http://dx.doi.org/10.1038/nbt.3796