Predicting drug–drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge

Drug–drug interactions (DDIs) may lead to adverse effects and potentially result in drug withdrawal from the market. Predicting DDIs during drug development would help reduce development costs and time by rigorous evaluation of drug candidates. The primary mechanisms of DDIs are based on pharmacokin...

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Detalles Bibliográficos
Autores principales: Takeda, Takako, Hao, Ming, Cheng, Tiejun, Bryant, Stephen H., Wang, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340788/
https://www.ncbi.nlm.nih.gov/pubmed/28316654
http://dx.doi.org/10.1186/s13321-017-0200-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340788/
https://www.ncbi.nlm.nih.gov/pubmed/28316654
http://dx.doi.org/10.1186/s13321-017-0200-8

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