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Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts

miRNAs are small 22-nucleotide RNAs that can post-transcriptionally regulate gene expression. It has been proposed that dietary plant miRNAs can enter the human bloodstream and regulate host transcripts; however, these findings have been widely disputed. We here conduct the first comprehensive meta-...

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Detalles Bibliográficos
Autores principales: Kang, Wenjing, Bang-Berthelsen, Claus Heiner, Holm, Anja, Houben, Anna J.S., Müller, Anne Holt, Thymann, Thomas, Pociot, Flemming, Estivill, Xavier, Friedländer, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340907/
https://www.ncbi.nlm.nih.gov/pubmed/28062594
http://dx.doi.org/10.1261/rna.059725.116