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A central role of Cwc25 in spliceosome dynamics during the catalytic phase of pre-mRNA splicing

Splicing of precursor mRNA occurs via two consecutive steps of transesterification reaction; both require ATP and several proteins. Despite the energy requirement in the catalytic phase, incubation of the purified spliceosome under proper ionic conditions can elicit competitive reversible transester...

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Detalles Bibliográficos
Autores principales:	Tseng, Chi-Kang, Chung, Che-Sheng, Chen, Hsin-Chou, Cheng, Soo-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340917/ https://www.ncbi.nlm.nih.gov/pubmed/28057857 http://dx.doi.org/10.1261/rna.059204.116

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