Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR

The double-stranded RNA (dsRNA)-activated protein kinase (PKR) senses dsRNA produced during viral infection and halts cellular protein synthesis to block viral replication. How basal PKR activity is controlled in the absence of infection was unclear until the recent identification of a potential end...

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Detalles Bibliográficos
Autores principales: Calderon, Brenda M., Conn, Graeme L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340918/
https://www.ncbi.nlm.nih.gov/pubmed/28069888
http://dx.doi.org/10.1261/rna.060269.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340918/
https://www.ncbi.nlm.nih.gov/pubmed/28069888
http://dx.doi.org/10.1261/rna.060269.116

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