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TRUB1 is the predominant pseudouridine synthase acting on mammalian mRNA via a predictable and conserved code

Following synthesis, RNA can be modified with over 100 chemically distinct modifications, which can potentially regulate RNA expression post-transcriptionally. Pseudouridine (Ψ) was recently established to be widespread and dynamically regulated on yeast mRNA, but less is known about Ψ presence, reg...

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Detalles Bibliográficos
Autores principales: Safra, Modi, Nir, Ronit, Farouq, Daneyal, Slutzkin, Ilya Vainberg, Schwartz, Schraga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340967/
https://www.ncbi.nlm.nih.gov/pubmed/28073919
http://dx.doi.org/10.1101/gr.207613.116