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Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response

Fasting elicits transcriptional programs in hepatocytes leading to glucose and ketone production. This transcriptional program is regulated by many transcription factors (TFs). To understand how this complex network regulates the metabolic response to fasting, we aimed at isolating the enhancers and...

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Detalles Bibliográficos
Autores principales: Goldstein, Ido, Baek, Songjoon, Presman, Diego M., Paakinaho, Ville, Swinstead, Erin E., Hager, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340970/
https://www.ncbi.nlm.nih.gov/pubmed/28031249
http://dx.doi.org/10.1101/gr.212175.116