UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experiments. Through a UMI, identical copies arising from distinct molecules can be distinguished from those arising through PCR amplification of the same molecule. Howeve...

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Detalles Bibliográficos
Autores principales: Smith, Tom, Heger, Andreas, Sudbery, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340976/
https://www.ncbi.nlm.nih.gov/pubmed/28100584
http://dx.doi.org/10.1101/gr.209601.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340976/
https://www.ncbi.nlm.nih.gov/pubmed/28100584
http://dx.doi.org/10.1101/gr.209601.116

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