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UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy
Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experiments. Through a UMI, identical copies arising from distinct molecules can be distinguished from those arising through PCR amplification of the same molecule. Howeve...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340976/ https://www.ncbi.nlm.nih.gov/pubmed/28100584 http://dx.doi.org/10.1101/gr.209601.116 |