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Zinc/copper imbalance reflects immune dysfunction in human leishmaniasis: an ex vivo and in vitro study

BACKGROUND: The process of elimination of intracellular pathogens, such as Leishmania, requires a Th1 type immune response, whereas a dominant Th2 response leads to exacerbated disease. Experimental human zinc deficiency decreases Th1 but not Th2 immune response. We investigated if zinc and copper l...

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Detalles Bibliográficos
Autores principales: Van Weyenbergh, Johan, Santana, Gisélia, D'Oliveira, Argemiro, Santos, Anibal F, Costa, Carlos H, Carvalho, Edgar M, Barral, Aldina, Barral-Netto, Manoel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC534101/
https://www.ncbi.nlm.nih.gov/pubmed/15546498
http://dx.doi.org/10.1186/1471-2334-4-50