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Zinc/copper imbalance reflects immune dysfunction in human leishmaniasis: an ex vivo and in vitro study
BACKGROUND: The process of elimination of intracellular pathogens, such as Leishmania, requires a Th1 type immune response, whereas a dominant Th2 response leads to exacerbated disease. Experimental human zinc deficiency decreases Th1 but not Th2 immune response. We investigated if zinc and copper l...
Autores principales: | Van Weyenbergh, Johan, Santana, Gisélia, D'Oliveira, Argemiro, Santos, Anibal F, Costa, Carlos H, Carvalho, Edgar M, Barral, Aldina, Barral-Netto, Manoel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC534101/ https://www.ncbi.nlm.nih.gov/pubmed/15546498 http://dx.doi.org/10.1186/1471-2334-4-50 |
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