Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene

EPH kinases and their ligands, ephrins (EFNs), have vital and diverse biological functions. We recently reported that Efnb3 gene deletion results in hypertension in female but not male mice. These data suggest that EFNB3 regulates blood pressure in a sex- and sex hormone-dependent way. In the presen...

Descripción completa

Detalles Bibliográficos
Autores principales: Tremblay, Johanne, Wang, Yujia, Raelson, John, Marois-Blanchet, Francois-Christophe, Wu, Zenghui, Luo, Hongyu, Bradley, Edward, Chalmers, John, Woodward, Mark, Harrap, Stephen, Hamet, Pavel, Wu, Jiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341021/
https://www.ncbi.nlm.nih.gov/pubmed/28272517
http://dx.doi.org/10.1038/srep44114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341021/
https://www.ncbi.nlm.nih.gov/pubmed/28272517
http://dx.doi.org/10.1038/srep44114

Ejemplares similares