Atomistic structural ensemble refinement reveals non-native structure stabilizes a sub-millisecond folding intermediate of CheY

The dynamics of globular proteins can be described in terms of transitions between a folded native state and less-populated intermediates, or excited states, which can play critical roles in both protein folding and function. Excited states are by definition transient species, and therefore are diff...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Jade, Nobrega, R. Paul, Schwantes, Christian, Kathuria, Sagar V., Bilsel, Osman, Matthews, C. Robert, Lane, T. J., Pande, Vijay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341065/
https://www.ncbi.nlm.nih.gov/pubmed/28272524
http://dx.doi.org/10.1038/srep44116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341065/
https://www.ncbi.nlm.nih.gov/pubmed/28272524
http://dx.doi.org/10.1038/srep44116

Ejemplares similares