Nucleic acid-based polymers effective against hepatitis B Virus infection in patients don’t harbor immunostimulatory properties in primary isolated liver cells

Nucleic acid polymers (NAPs) block the release of subviral particles from hepatocytes, a mechanism consistent with their antiviral activity against hepatitis B virus (HBV) in patients. Analysis of immunostimulatory properties of NAPs were conducted with several NAP species: REP 2006, the prototypic...

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Detalles Bibliográficos
Autores principales: Real, Catherine Isabell, Werner, Melanie, Paul, Andreas, Gerken, Guido, Schlaak, Joerg Friedrich, Vaillant, Andrew, Broering, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341074/
https://www.ncbi.nlm.nih.gov/pubmed/28272460
http://dx.doi.org/10.1038/srep43838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341074/
https://www.ncbi.nlm.nih.gov/pubmed/28272460
http://dx.doi.org/10.1038/srep43838

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