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Amigo2-upregulation in Tumour Cells Facilitates Their Attachment to Liver Endothelial Cells Resulting in Liver Metastases

Since liver metastasis is the main cause of death in cancer patients, we attempted to identify the driver gene involved. QRsP-11 fibrosarcoma cells were injected into the spleens of syngeneic mice to isolate tumour sub-populations that colonize the liver. Cells from liver metastatic nodules were est...

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Detalles Bibliográficos
Autores principales: Kanda, Yusuke, Osaki, Mitsuhiko, Onuma, Kunishige, Sonoda, Ayana, Kobayashi, Masanobu, Hamada, Junichi, Nicolson, Garth L., Ochiya, Takahiro, Okada, Futoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341090/
https://www.ncbi.nlm.nih.gov/pubmed/28272394
http://dx.doi.org/10.1038/srep43567