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Amigo2-upregulation in Tumour Cells Facilitates Their Attachment to Liver Endothelial Cells Resulting in Liver Metastases
Since liver metastasis is the main cause of death in cancer patients, we attempted to identify the driver gene involved. QRsP-11 fibrosarcoma cells were injected into the spleens of syngeneic mice to isolate tumour sub-populations that colonize the liver. Cells from liver metastatic nodules were est...
Autores principales: | Kanda, Yusuke, Osaki, Mitsuhiko, Onuma, Kunishige, Sonoda, Ayana, Kobayashi, Masanobu, Hamada, Junichi, Nicolson, Garth L., Ochiya, Takahiro, Okada, Futoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341090/ https://www.ncbi.nlm.nih.gov/pubmed/28272394 http://dx.doi.org/10.1038/srep43567 |
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