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Effects of different kinds of essentiality on sequence evolution of human testis proteins

We asked if essentiality for either fertility or viability differentially affects sequence evolution of human testis proteins. Based on murine knockout data, we classified a set of 965 proteins expressed in human seminiferous tubules into three categories: proteins essential for prepubertal survival...

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Detalles Bibliográficos
Autores principales: Schumacher, Julia, Zischler, Hans, Herlyn, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341092/
https://www.ncbi.nlm.nih.gov/pubmed/28272493
http://dx.doi.org/10.1038/srep43534