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Enhanced Dupuytren's disease fibroblast populated collagen lattice contraction is independent of endogenous active TGF-β(2)
BACKGROUND: Dupuytren's disease (DD) is a debilitating fibro-proliferative disorder of the hand characterized by the appearance of fibrotic lesions (nodules and cords) leading to flexion contractures of the fingers and loss of hand function. Although the molecular mechanism of DD is unknown, it...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC534110/ https://www.ncbi.nlm.nih.gov/pubmed/15541177 http://dx.doi.org/10.1186/1471-2474-5-41 |