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DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms

BACKGROUND: Duodenal cytochrome b (DCYTB) is a ferrireductase that functions together with divalent metal transporter 1 (DMT1) to mediate dietary iron reduction and uptake in the duodenum. DCYTB is also a member of a 16-gene iron regulatory gene signature (IRGS) that predicts metastasis-free surviva...

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Detalles Bibliográficos
Autores principales: Lemler, David J., Lynch, Miranda L., Tesfay, Lia, Deng, Zhiyong, Paul, Bibbin T., Wang, Xiaohong, Hegde, Poornima, Manz, David H., Torti, Suzy V., Torti, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341190/
https://www.ncbi.nlm.nih.gov/pubmed/28270217
http://dx.doi.org/10.1186/s13058-017-0814-9