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DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms
BACKGROUND: Duodenal cytochrome b (DCYTB) is a ferrireductase that functions together with divalent metal transporter 1 (DMT1) to mediate dietary iron reduction and uptake in the duodenum. DCYTB is also a member of a 16-gene iron regulatory gene signature (IRGS) that predicts metastasis-free surviva...
Autores principales: | Lemler, David J., Lynch, Miranda L., Tesfay, Lia, Deng, Zhiyong, Paul, Bibbin T., Wang, Xiaohong, Hegde, Poornima, Manz, David H., Torti, Suzy V., Torti, Frank M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341190/ https://www.ncbi.nlm.nih.gov/pubmed/28270217 http://dx.doi.org/10.1186/s13058-017-0814-9 |
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