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Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer

Increased collagen expression in tumors is associated with increased risk of metastasis, and triple-negative breast cancer (TNBC) has the highest propensity to develop distant metastases when there is evidence of central fibrosis. Transforming growth factor-β (TGF-β) ligands regulated by cancer-asso...

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Detalles Bibliográficos
Autores principales: Takai, Ken, Le, Annie, Weaver, Valerie M., Werb, Zena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341254/
https://www.ncbi.nlm.nih.gov/pubmed/27756881
http://dx.doi.org/10.18632/oncotarget.12658