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Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer
Increased collagen expression in tumors is associated with increased risk of metastasis, and triple-negative breast cancer (TNBC) has the highest propensity to develop distant metastases when there is evidence of central fibrosis. Transforming growth factor-β (TGF-β) ligands regulated by cancer-asso...
Autores principales: | Takai, Ken, Le, Annie, Weaver, Valerie M., Werb, Zena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341254/ https://www.ncbi.nlm.nih.gov/pubmed/27756881 http://dx.doi.org/10.18632/oncotarget.12658 |
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