Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

Cisplatin is an effective breast cancer drug but resistance often develops over prolonged chemotherapy. Therefore, we performed a candidate approach RNAi screen in combination with cisplatin treatment to identify molecular pathways conferring survival advantages. The screen identified ATP7A as a the...

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Detalles Bibliográficos
Autores principales: Chisholm, Cristine L., Wang, Haitao, Wong, Ada Hang-Heng, Vazquez-Ortiz, Guelaguetza, Chen, Weiping, Xu, Xiaoling, Deng, Chu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341295/
https://www.ncbi.nlm.nih.gov/pubmed/27806319
http://dx.doi.org/10.18632/oncotarget.12992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341295/
https://www.ncbi.nlm.nih.gov/pubmed/27806319
http://dx.doi.org/10.18632/oncotarget.12992

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