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RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells

c-Kit is a tyrosine kinase receptor important for gametogenesis, hematopoiesis, melanogenesis and mast cell biology. Dysregulation of c-Kit function is oncogenic and its expression in the stem cell niche of a number of tissues has underlined its relevance for regenerative medicine and hematopoietic...

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Detalles Bibliográficos
Autores principales: Puverel, Sandrine, Kiris, Erkan, Singh, Satyendra, Klarmann, Kimberly D., Coppola, Vincenzo, Keller, Jonathan R., Tessarollo, Lino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341297/
https://www.ncbi.nlm.nih.gov/pubmed/27835883
http://dx.doi.org/10.18632/oncotarget.13198