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RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells
c-Kit is a tyrosine kinase receptor important for gametogenesis, hematopoiesis, melanogenesis and mast cell biology. Dysregulation of c-Kit function is oncogenic and its expression in the stem cell niche of a number of tissues has underlined its relevance for regenerative medicine and hematopoietic...
Autores principales: | Puverel, Sandrine, Kiris, Erkan, Singh, Satyendra, Klarmann, Kimberly D., Coppola, Vincenzo, Keller, Jonathan R., Tessarollo, Lino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341297/ https://www.ncbi.nlm.nih.gov/pubmed/27835883 http://dx.doi.org/10.18632/oncotarget.13198 |
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