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Selective activation of miRNAs of the primate-specific chromosome 19 miRNA cluster (C19MC) in cancer and stem cells and possible contribution to regulation of apoptosis

BACKGROUND: The human chromosome 19 miRNA cluster (C19MC) of 43 genes is a primate-specific miRNA cluster that may have biological significance in the genetic complexity of the primate. Despite previous reports on individual C19MC miRNA expression in cancer and stem cells, systematic studies on C19M...

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Detalles Bibliográficos
Autores principales: Nguyen, Phan Nguyen Nhi, Huang, Chiu-Jung, Sugii, Shigeki, Cheong, Soon Keng, Choo, Kong Bung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341377/
https://www.ncbi.nlm.nih.gov/pubmed/28270145
http://dx.doi.org/10.1186/s12929-017-0326-z