Cargando…

Characterization of the HLA-DRβ1 third hypervariable region amino acid sequence according to charge and parental inheritance in systemic sclerosis

BACKGROUND: Specific HLA class II alleles are associated with systemic sclerosis (SSc) risk, clinical characteristics, and autoantibodies. HLA nomenclature initially developed with antibodies as typing reagents defining DRB1 allele groups. However, alleles from different DRB1 allele groups encode th...

Descripción completa

Detalles Bibliográficos
Autores principales: Gentil, Coline A., Gammill, Hilary S., Luu, Christine T., Mayes, Maureen D., Furst, Dan E., Nelson, J. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341397/
https://www.ncbi.nlm.nih.gov/pubmed/28270189
http://dx.doi.org/10.1186/s13075-017-1253-9