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Characterization of the HLA-DRβ1 third hypervariable region amino acid sequence according to charge and parental inheritance in systemic sclerosis
BACKGROUND: Specific HLA class II alleles are associated with systemic sclerosis (SSc) risk, clinical characteristics, and autoantibodies. HLA nomenclature initially developed with antibodies as typing reagents defining DRB1 allele groups. However, alleles from different DRB1 allele groups encode th...
Autores principales: | Gentil, Coline A., Gammill, Hilary S., Luu, Christine T., Mayes, Maureen D., Furst, Dan E., Nelson, J. Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341397/ https://www.ncbi.nlm.nih.gov/pubmed/28270189 http://dx.doi.org/10.1186/s13075-017-1253-9 |
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