Cargando…

Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitor

BACKGROUND: Drugs often kill some cancer cells while others survive. This stochastic outcome is seen even in clonal cells grown under the same conditions. Understanding the molecular reasons for this stochastic outcome is a current challenge, which requires studying the proteome at the single cell l...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimmer, Anat, Amar-Farkash, Shlomit, Danon, Tamar, Alon, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341406/
https://www.ncbi.nlm.nih.gov/pubmed/28270142
http://dx.doi.org/10.1186/s12918-017-0410-8