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Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitor
BACKGROUND: Drugs often kill some cancer cells while others survive. This stochastic outcome is seen even in clonal cells grown under the same conditions. Understanding the molecular reasons for this stochastic outcome is a current challenge, which requires studying the proteome at the single cell l...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341406/ https://www.ncbi.nlm.nih.gov/pubmed/28270142 http://dx.doi.org/10.1186/s12918-017-0410-8 |