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Regulating retrotransposon activity through the use of alternative transcription start sites

Retrotransposons, the ancestors of retroviruses, have the potential for gene disruption and genomic takeover if not kept in check. Paradoxically, although host cells repress these elements by multiple mechanisms, they are transcribed and are even activated under stress conditions. Here, we describe...

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Detalles Bibliográficos
Autores principales: Persson, Jenna, Steglich, Babett, Smialowska, Agata, Boyd, Mette, Bornholdt, Jette, Andersson, Robin, Schurra, Catherine, Arcangioli, Benoit, Sandelin, Albin, Nielsen, Olaf, Ekwall, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341516/
https://www.ncbi.nlm.nih.gov/pubmed/26902262
http://dx.doi.org/10.15252/embr.201541866