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Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEX

Conventional cell-SELEX aims to isolate aptamers to a single unique target bacteria species. We propose a method to isolate single-stranded DNA aptamers that have broad reactivity to multiple bacterial targets belonging to different genera. The key of the proposed method is that targets of interest...

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Detalles Bibliográficos
Autores principales: Song, Min Young, Nguyen, Dung, Hong, Seok Won, Kim, Byoung Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341558/
https://www.ncbi.nlm.nih.gov/pubmed/28272554
http://dx.doi.org/10.1038/srep43641