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Broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-SELEX
Conventional cell-SELEX aims to isolate aptamers to a single unique target bacteria species. We propose a method to isolate single-stranded DNA aptamers that have broad reactivity to multiple bacterial targets belonging to different genera. The key of the proposed method is that targets of interest...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341558/ https://www.ncbi.nlm.nih.gov/pubmed/28272554 http://dx.doi.org/10.1038/srep43641 |