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Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways

Cells adopt distinct signaling pathways to optimize cell locomotion in different physical microenvironments. However, the underlying mechanism that enables cells to sense and respond to physical confinement is unknown. Using microfabricated devices and substrate-printing methods along with FRET-base...

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Detalles Bibliográficos
Autores principales: Hung, Wei-Chien, Yang, Jessica R., Yankaskas, Christopher L., Wong, Bin Sheng, Wu, Pei-Hsun, Pardo-Pastor, Carlos, Serra, Selma A., Chiang, Meng-Jung, Gu, Zhizhan, Wirtz, Denis, Valverde, Miguel A., Yang, Joy T., Zhang, Jin, Konstantopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341576/
https://www.ncbi.nlm.nih.gov/pubmed/27160899
http://dx.doi.org/10.1016/j.celrep.2016.04.035