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Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways
Cells adopt distinct signaling pathways to optimize cell locomotion in different physical microenvironments. However, the underlying mechanism that enables cells to sense and respond to physical confinement is unknown. Using microfabricated devices and substrate-printing methods along with FRET-base...
Autores principales: | Hung, Wei-Chien, Yang, Jessica R., Yankaskas, Christopher L., Wong, Bin Sheng, Wu, Pei-Hsun, Pardo-Pastor, Carlos, Serra, Selma A., Chiang, Meng-Jung, Gu, Zhizhan, Wirtz, Denis, Valverde, Miguel A., Yang, Joy T., Zhang, Jin, Konstantopoulos, Konstantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341576/ https://www.ncbi.nlm.nih.gov/pubmed/27160899 http://dx.doi.org/10.1016/j.celrep.2016.04.035 |
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