Preloading with Unlabeled CA19.9 Targeted Human Monoclonal Antibody Leads to Improved PET Imaging with (89)Zr-5B1

[Image: see text] CA19.9 is one of the most commonly occurring and highest density antigens in >90% of pancreatic cancers, making it an excellent target for monoclonal antibody (mAb)-based imaging and therapy applications. Preloading of unlabeled antibodies to enhance targeting of a radiolabeled...

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Detalles Bibliográficos
Autores principales: Houghton, Jacob L., Abdel-Atti, Dalya, Scholz, Wolfgang W., Lewis, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341702/
https://www.ncbi.nlm.nih.gov/pubmed/28191976
http://dx.doi.org/10.1021/acs.molpharmaceut.6b01130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341702/
https://www.ncbi.nlm.nih.gov/pubmed/28191976
http://dx.doi.org/10.1021/acs.molpharmaceut.6b01130

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