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New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status

We synthesized, characterized and tested in a panel of cancer cell lines, nine new bipyridine gold(III) dithiocarbamate-containing complexes. In vitro studies demonstrated that compounds 1, 2, 4, 5, 7 and 8 were the most cytotoxic in prostate, breast, ovarian cancer cell lines and in Hodgkin lymphom...

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Detalles Bibliográficos
Autores principales: Altaf, Muhammad, Monim-ul-Mehboob, Muhammad, Kawde, Abdel-Nasser, Corona, Giuseppe, Larcher, Roberto, Ogasawara, Marcia, Casagrande, Naike, Celegato, Marta, Borghese, Cinzia, Siddik, Zahid H., Aldinucci, Donatella, Isab, Anvarhusein A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341752/
https://www.ncbi.nlm.nih.gov/pubmed/27888799
http://dx.doi.org/10.18632/oncotarget.13448