Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis

The Smyd2 protein (Set- and Mynd domain containing protein 2) is a methyl-transferase that can modify both histones and cytoplasmic proteins. Smyd2 is over-expressed in several cancer types and was shown to be limiting for tumor development in the pancreas. However, genetic evidence for a role of Sm...

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Detalles Bibliográficos
Autores principales: Bagislar, Sevgi, Sabò, Arianna, Kress, Theresia R., Doni, Mirko, Nicoli, Paola, Campaner, Stefano, Amati, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341809/
https://www.ncbi.nlm.nih.gov/pubmed/27655694
http://dx.doi.org/10.18632/oncotarget.12012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341809/
https://www.ncbi.nlm.nih.gov/pubmed/27655694
http://dx.doi.org/10.18632/oncotarget.12012

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