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Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis
The Smyd2 protein (Set- and Mynd domain containing protein 2) is a methyl-transferase that can modify both histones and cytoplasmic proteins. Smyd2 is over-expressed in several cancer types and was shown to be limiting for tumor development in the pancreas. However, genetic evidence for a role of Sm...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341809/ https://www.ncbi.nlm.nih.gov/pubmed/27655694 http://dx.doi.org/10.18632/oncotarget.12012 |