NOX4 downregulation leads to senescence of human vascular smooth muscle cells

Senescence is a stress response characterized by an irreversible growth arrest and alterations in certain cell functions. It is believed that both double-strand DNA breaks (DSB) and increased ROS level are the main culprit of senescence. Excessive ROS production is also particularly important in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Przybylska, Dorota, Janiszewska, Dorota, Goździk, Aleksandra, Bielak-Zmijewska, Anna, Sunderland, Piotr, Sikora, Ewa, Mosieniak, Grażyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341811/
https://www.ncbi.nlm.nih.gov/pubmed/27655718
http://dx.doi.org/10.18632/oncotarget.12079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341811/
https://www.ncbi.nlm.nih.gov/pubmed/27655718
http://dx.doi.org/10.18632/oncotarget.12079

Ejemplares similares