Cargando…

NOX4 downregulation leads to senescence of human vascular smooth muscle cells

Senescence is a stress response characterized by an irreversible growth arrest and alterations in certain cell functions. It is believed that both double-strand DNA breaks (DSB) and increased ROS level are the main culprit of senescence. Excessive ROS production is also particularly important in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Przybylska, Dorota, Janiszewska, Dorota, Goździk, Aleksandra, Bielak-Zmijewska, Anna, Sunderland, Piotr, Sikora, Ewa, Mosieniak, Grażyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341811/ https://www.ncbi.nlm.nih.gov/pubmed/27655718 http://dx.doi.org/10.18632/oncotarget.12079

Ejemplares similares

Curcumin elevates sirtuin level but does not postpone in vitro senescence of human cells building the vasculature
por: Grabowska, Wioleta, et al.
Publicado: (2016)

A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta
por: Bielak-Zmijewska, Anna, et al.
Publicado: (2013)

Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner
por: Grabowska, Wioleta, et al.
Publicado: (2015)

Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence
por: Grabowska, Wioleta, et al.
Publicado: (2019)

Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells
por: Piszczatowska, Katarzyna, et al.
Publicado: (2020)

Cellular Senescence in Brain Aging
por: Sikora, Ewa, et al.
Publicado: (2021)

DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Epigenetic clock analyses of cellular senescence and ageing
por: Lowe, Donna, et al.
Publicado: (2016)

MeCP2 mediated dysfunction in senescent EPCs
por: Wang, Chunli, et al.
Publicado: (2017)

Run-on of germline apoptosis promotes gonad senescence in C. elegans
por: de la Guardia, Yila, et al.
Publicado: (2016)

RNA methyltransferase NSUN2 promotes stress-induced HUVEC senescence
por: Cai, Xiaoyu, et al.
Publicado: (2016)

Gadd45b deficiency promotes premature senescence and skin aging
por: Magimaidas, Andrew, et al.
Publicado: (2016)

Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation
por: Xie, Jun, et al.
Publicado: (2017)

Senoptosis: non-lethal DNA cleavage as a route to deep senescence
por: Studencka, Maja, et al.
Publicado: (2017)

Drug-induced premature senescence model in human dental follicle stem cells
por: Zhai, Yuanfen, et al.
Publicado: (2016)

ATF6α regulates morphological changes associated with senescence in human fibroblasts
por: Druelle, Clémentine, et al.
Publicado: (2016)

Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway
por: Kinoshita, Daisuke, et al.
Publicado: (2017)

Aging with ING: a comparative study of different forms of stress induced premature senescence
por: Rajarajacholan, Uma Karthika, et al.
Publicado: (2015)

Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity
por: Özcan, Servet, et al.
Publicado: (2015)

BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21
por: Lee, Hyemin, et al.
Publicado: (2016)

A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence
por: Ghosh, Asish K., et al.
Publicado: (2016)

XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence
por: Heo, Jong-Ik, et al.
Publicado: (2016)

Identification of the lncRNA, AK156230, as a novel regulator of cellular senescence in mouse embryonic fibroblasts
por: Chen, Yu-ning, et al.
Publicado: (2016)

MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence
por: Zhang, Jia-an, et al.
Publicado: (2016)

Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice
por: Lettieri-Barbato, Daniele, et al.
Publicado: (2017)

The Role of Curcumin in the Modulation of Ageing
por: Bielak-Zmijewska, Anna, et al.
Publicado: (2019)

Downregulation of protein kinase CK2 activity induces age-related biomarkers in C. elegans
por: Park, Jeong-Hwan, et al.
Publicado: (2017)

A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells
por: Huang, Peixin, et al.
Publicado: (2015)

Activation of bitter taste receptors (tas2rs) relaxes detrusor smooth muscle and suppresses overactive bladder symptoms
por: Zhai, Kui, et al.
Publicado: (2016)

The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts
por: Ramdzan, Zubaidah M., et al.
Publicado: (2015)

Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells
por: Tsuchihashi, Nana Akagi, et al.
Publicado: (2014)

Protease activated receptor-1 regulates macrophage-mediated cellular senescence: a risk for idiopathic pulmonary fibrosis
por: Lin, Cong, et al.
Publicado: (2015)

Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence
por: Germanio, Clara Di, et al.
Publicado: (2016)

Ginsenoside Rg3 inhibits the senescence of prostate stromal cells through down-regulation of interleukin 8 expression
por: Peng, Yanfei, et al.
Publicado: (2017)

Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells
por: Capasso, Stefania, et al.
Publicado: (2015)

GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells
por: Park, Hyejin, et al.
Publicado: (2016)

Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells
por: Liu, Zhao, et al.
Publicado: (2016)

Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence()
por: Mosieniak, Grazyna, et al.
Publicado: (2015)

c-Maf regulates pluripotency genes, proliferation/self-renewal, and lineage commitment in ROS-mediated senescence of human mesenchymal stem cells
por: Chen, Pei-Min, et al.
Publicado: (2015)

The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain
por: Wang, Jianhui, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_09su3htl4571bgp5dr3a133nq9