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Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells

Studies have investigated the tumor suppressive role of rottlerin in carcinogenesis. However, the molecular mechanisms of rottlerin-induced anti-tumor activity are largely unclear. Skp2 (S-phase kinase associated protein 2) has been validated to play an oncogenic role in a variety of human malignanc...

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Detalles Bibliográficos
Autores principales: Yin, Xuyuan, Zhang, Yu, Su, Jingna, Hou, Yingying, Wang, Lixia, Ye, Xiantao, Zhao, Zhe, Zhou, Xiuxia, Li, Yali, Wang, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341817/
https://www.ncbi.nlm.nih.gov/pubmed/27582552
http://dx.doi.org/10.18632/oncotarget.11614