Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea

Hair cell (HC) loss is the main cause of permanent hearing loss in mammals. Previous studies have reported that in neonatal mice cochleae, Wnt activation promotes supporting cell (SC) proliferation and Notch inhibition promotes the trans-differentiation of SCs into HCs. However, Wnt activation alone...

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Detalles Bibliográficos
Autores principales: Ni, Wenli, Zeng, Shan, Li, Wenyan, Chen, Yan, Zhang, Shasha, Tang, Mingliang, Sun, Shan, Chai, Renjie, Li, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341835/
https://www.ncbi.nlm.nih.gov/pubmed/27564256
http://dx.doi.org/10.18632/oncotarget.11479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341835/
https://www.ncbi.nlm.nih.gov/pubmed/27564256
http://dx.doi.org/10.18632/oncotarget.11479

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