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Identification of SHCBP1 as a novel downstream target gene of SS18-SSX1 and its functional analysis in progression of synovial sarcoma

The SS18-SSX1 fusion gene has been shown to play important roles in the development of synovial sarcoma (SS), but the underlying molecular mechanisms and its downstream target genes are still not clear. Here SHC SH2-domain binding protein 1 (SHCBP1) was identified and validated to be a novel downstr...

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Detalles Bibliográficos
Autores principales: Peng, Changliang, Zhao, Hui, Chen, Wei, Song, Yan, Wang, Xiaoying, Li, Ji, Qiao, Yong, Wu, Dongjin, Ma, Shengzhong, Wang, Xiuwen, Gao, Chunzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341840/
https://www.ncbi.nlm.nih.gov/pubmed/27572315
http://dx.doi.org/10.18632/oncotarget.11651