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eIF4E promotes tumorigenesis and modulates chemosensitivity to cisplatin in esophageal squamous cell carcinoma

Patients with esophageal squamous cell cancer are often diagnosed with advanced diseases that respond poorly to chemotherapy. Overexpression of eIF4E leads to enhance the translation of key malignancy-related proteins and enabling tumor growth and chemoresistance in a variety of human malignancies,...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Li, Rong, Zhao, Hui, Deng, Juan, Long, Ying, Shuai, Meng-ting, Li, Qian, Gu, Huan, Chen, Ya-qi, Leng, Ai-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341842/
https://www.ncbi.nlm.nih.gov/pubmed/27588477
http://dx.doi.org/10.18632/oncotarget.11694