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Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway
There is an urgent need for new therapeutic strategies for patients with glioblastoma multiforme (GBM). Previous studies have shown that berberine (BBR), a natural plant alkaloid, has potent anti-tumor activity. However, the mechanisms leading to cancer cell death have not been clearly elucidated. I...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341849/ https://www.ncbi.nlm.nih.gov/pubmed/27557493 http://dx.doi.org/10.18632/oncotarget.11396 |