Cargando…

Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway

There is an urgent need for new therapeutic strategies for patients with glioblastoma multiforme (GBM). Previous studies have shown that berberine (BBR), a natural plant alkaloid, has potent anti-tumor activity. However, the mechanisms leading to cancer cell death have not been clearly elucidated. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jiwei, Qi, Qichao, Feng, Zichao, Zhang, Xin, Huang, Bin, Chen, Anjing, Prestegarden, Lars, Li, Xingang, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341849/
https://www.ncbi.nlm.nih.gov/pubmed/27557493
http://dx.doi.org/10.18632/oncotarget.11396